Partners Publications (with downloadable PDFs)

Grant RW, Buse JB, Meigs JB. University HealthSystem Consortium (UHC) Diabetes Benchmarking Project Team. Quality of diabetes care in U.S. academic medical centers: Low rates of medical regimen change. Diabetes Care. 2005 Feb;28(2):337-442.

Grant RW, Cagliero E, Dubey AK, Gildesgame C, Chueh HC, Barry MJ, Singer DE, Nathan DM, Meigs JB. Clinical inertia in the management of Type 2 diabetes metabolic risk factors. Diabet Med. 2004 Feb;21(2):150-5.

Grant RW, Cagliero E, Murphy-Sheehy P, Singer DE, Nathan DM, Meigs JB. Comparison of hyperglycemia, hypertension, and hypercholesterolemia management in patients with type 2 diabetes. Am J Med. 2002 Jun 1;112(8):603-9.

Grant RW, Cagliero E, Sullivan CM, Dubey AK, Estey GA, Weil EM, Gesmundo J, Nathan DM, Singer DE, Chueh HC, Meigs JB. A controlled trial of population management: Diabetes mellitus: Putting evidence into practice (DM-PEP). Diabetes Care. 2004 Oct;27(10):2299-305.

Grant RW, Devita NG, Singer DE, Meigs JB. Polypharmacy and medication adherence in patients with type 2 diabetes. Diabetes Care. 2003 May;26(5):1408-12.

Grant RW, O'Leary KM, Weilburg JB, Singer DE, Meigs JB. Impact of concurrent medication use on statin adherence and refill persistence. Arch Intern Med. 2004 Nov 22;164(21):2343-8.

Grant RW, Pirraglia PA, Meigs JB, Singer DE. Trends in complexity of diabetes care in the United States from 1991 to 2000. Arch Intern Med. 2004 May;164(24):1134-9.

Lester WT, Grant R, Barnett GO, Chueh H. Facilitated lipid management using interactive e-mail: Preliminary results of a randomized controlled trial. Medinfo. 2004;2004:232-6.

Meigs JB. Metabolic Syndrome: In search of a clinical role. Diabetes Care. 2004 Nov;27(11):2761-63.

Meigs JB, Cagliero E, Dubey A, Murphy-Sheehy P, Gildesgame C, Chueh H, Barry MJ, Singer DE, Nathan DM. A controlled trial of web-based diabetes disease management: The MGH diabetes primary care improvement project. Diabetes Care. 2003 Mar;26(3):750-7.

Meigs JB, Williams K, Sullivan LM, Hunt KJ, Haffner SM, Stern MP, Gonzalez Villalpando C, Perhanidis JS, Nathan DM, D'Agostino RB Jr, D'Agostino RB Sr, Wilson PW. Using metabolic syndrome traits for efficient detection of impaired glucose tolerance. Diabetes Care. 2004 Jun;27(6):1417-26.

Wexler DJ, Grant RW, Meigs JB, Nathan DM, Cagliero E. Sex disparities in treatment of cardiac risk factors in patients with type 2 diabetes. Diabetes Care. 2005 Mar;28(3):514-20.

Testing of Diabetes and Its Complications

Godine JE, Hurxthal K, Nathan DM. Bedside capillary glucose measurement by staff nurses in a general hospital. Am J Med. 1986; 80:803-806.

Nathan DM, Fogel HA, Godine JE, Lou PL, D’Amico DJ, Regan CDJ, Topping TM. The role of the internist in evaluating diabetic retinopathy. Diabetes Care 1991; 14:26-33.

Nathan DM, Rosenbaum C, Protasowicki VD. Single void urine samples can be used to estimate quantitative microalbuminuria. Diabetes Care 1987: 10:414-418.

Nathan DM, Singer DE, Hurxthal K, Goodson JD. The clinical information value of the glycosylated hemoglobin assay. New Engl J Med 1984; 310:341-346.

Singer DE, Nathan DM, Fogel HA, Schachat AP. Screening for diabetic retinopathy. Ann Int Med. 1992; 116:660-671.

Treatment of Type 1 Diabetes

Lachin JM, Genuth S, Cleary P, Davis MD, Nathan DM for the EDIC Research Group. Retinopathy and nephropathy in patients with Type 1 diabetes four years after a trial of intensive therapy. N Engl J Med 2000; 342:381-9.

Nathan DM. Isolated pancreas transplantation for type 1 diabetes: a doctor’s dilemma. JAMA 2003; 290: 2861-2863.
Nathan DM, Crofford OB, Genuth S, Lachin J , Rand L, Davis M, Siebert C, Cleary PA for the DCCT Research Group. The effect of intensive diabetes treatment on the development and progression of long-term complications in insulin-dependent diabetes mellitus: The Diabetes Control and Complications Trial. New Engl J Med 1993;329:978-986.

Nathan DM, Fogel HA, Norman D, Russell PS, Tolkoff-Rubin N, Delmonico FL, Auchincloss H, Camuso J, Cosimi AB. Long-term metabolic and quality of life results with pancreatic/renal transplantation in IDDM. Transplantation 1991; 52:85-91.

Nathan DM, Godine JE, Gauthier-Kelley C, Kawahara D, Grinvalsky M. Ice cream in the diet of insulin-dependent diabetic patients. JAMA 1984; 251:2825-2827.

Nathan DM, Madnek SF, Delahanty L. Programming pre-exercise snacks to prevent post-exercise hypoglycemia in intensively treated insulin-dependent diabetes. Ann Int Med. 1985; 102:483-486.

Treatment of Type 2 Diabetes

Cagliero E, Levina E, Nathan DM. Immediate feedback of HbA1c levels improves glycemic control in Type 1 and insulin-treated Type 2 diabetic patients. Diabetes Care 1999;22:1785-89.

Nathan DM. Initial management of glycemia in type 2 diabetes mellitus. N Engl J Med 2002; 347:1342-1349.

Nathan DM, Roussell A, Godine JE. Glyburide or insulin for metabolic control in non- insulin-dependent diabetes mellitus: A randomized double-blind study. Ann Int Med. 1988; 334-340.

Diabetes Complications: Microvascular

Genuth S, Lachin J, Cleary, P, Nathan DM for the DCCT/EDIC Research Group. Effect of intensive therapy on the microvascular complications of type 1 diabetes mellitus. JAMA 2002;287:2563-2569.

Lachin, J, Genuth S, Nathan DM for the DCCT Research Group. The absence of a glycemic threshold for the development of long-term complications. Diabetes 1996; 45:1289-1298.

Nathan DM. Long-term complications of diabetes mellitus. New Engl J Med 1993;328;676-685.

Steffes MW, Chavers BM, Molitch ME, Cleary PA, Lachin JM, Genuth S and Nathan DM for the DCCT/EDIC Research Group. Sustained effect of intensive treatment of type 1 diabetes mellitus on development and progression of diabetic nephropathy. JAMA 2003; 290:2159-2167.

Diabetes Complications: Cardiovascular

Blake DR, Meigs JB, Muller DC, Najjar SS, Andres RA, Nathan DM. Impaired glucose tolerance, but not fasting glucose, is associated with increased levels of coronary heart risk factors: results from the Baltimore Longitudinal Study on Aging. Diabetes 2004; 53: 2095.

Cagliero E, Apruzzese W, Perlmutter GS, Nathan DM. Musculoskeletal disorders of the hand and shoulder in patients with diabetes mellitus. Am J Med 2002; 112: 487-90.

Meigs JB, D’Agostino RB, Wilson PWF, Cupples LA, Nathan DM, Singer DE.Risk variable clustering in the insulin resistance syndrome: the Framingham Offspring Study. Diabetes 1997;46: 1594-1600.

Meigs JB, Nathan DM, D’Agostino RB, Wilson PWF. Fasting and postchallenge glycemia and cardiovascular disease risk: the Framingham Offspring Study. Diabetes Care 2002; 25:1845-50.

Meigs JB, Nathan DM, Wilson PWF, Cupples LA, Singer DE. Metabolic risk factors worsen continuously across the spectrum of nondiabetic glucose tolerance. The Framingham Offspring Study. Ann Int Med 1998; 128:524-33.

Nathan DM, Lachin J, Cleary P, Orchard T, Brillon DJ, Backlund J-Y, O’Leary DH, and Genuth S for the DCCT/EDIC Research Group. Intensive diabetes therapy and carotid intima-media thickness in type 1 diabetes mellitus. N Engl J Med 2003;348:2290-9.

Singer DE, Nathan DM, Anderson KM, Wilson PWF, Evans JC. The association of hemoglobin A1C with prevalent cardiovascular disease in the original cohort of the Framingham Heart Study. Diabetes 1992; 41:202-208.

Prevention

Knowler WC, Barrett-Connor E, Fowler S, Hamman R, Lachin J, Walker E, Nathan DM for the DPP Research Group. Reduction in incidence of Type 2 diabetes with life-style intervention or metformin. N Engl J Med 2002; 346:393-403.

Improvement in Diabetes Care/Quality Improvement

Nathan DM. The impact of clinical trials on the treatment of diabetes mellitus. JCEM 2002;87:1929-1935.